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Yangambin

Product Name
Yangambin
CAS No.
13060-14-5
Chemical Name
Yangambin
Synonyms
C10894;YANGAMBIN;(+)-Yangabin;Lrioresinol B dimethyl ether;Lirioresinol B dimethyl ether;(+)-O,O-Dimethyl lirioresinol B;yangambin/Lrioresinol B dimethyl ether;inhibit,Calcium Channel,Yangambin,Ca channels,Ca2+ channels,Inhibitor;(1β,5β)-2β,6β-Bis(3,4,5-trimethoxyphenyl)-3,7-dioxabicyclo[3.3.0]octane;(1S,3aR,4S,6aR)-Tetrahydro-1,4-bis(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan
CBNumber
CB31246402
Molecular Formula
C24H30O8
Formula Weight
446.49
MOL File
13060-14-5.mol
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Yangambin Property

Melting point:
105-106 °C
Boiling point:
556.1±50.0 °C(Predicted)
Density 
1.183±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0032586
Product name
Yangambin
Packaging
5mg
Price
$880
Updated
2021/12/16
ChemScene
Product number
CS-0032586
Product name
Yangambin
Packaging
10mg
Price
$1500
Updated
2021/12/16
Arctom
Product number
CFN96416
Product name
Yangambin
Purity
≥98%
Packaging
5mg
Price
$398
Updated
2021/12/16
Crysdot
Product number
CD32002589
Product name
Yangambin
Purity
95+%
Packaging
5mg
Price
$723
Updated
2021/12/16
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Yangambin Chemical Properties,Usage,Production

Uses

Yangambin is one of the active ingredients of Radix Stellerae Chamaejasmes, which is bitter in nature and taste, and is highly toxic. It has the effects of severe diarrhea, prevent decay, and swelling. It is clinically used for erysipelas, mammary carbuncle, swollen mumps (mumps), yellow water sores, and acne.

Definition

ChEBI: Yangambin is a lignan.

Biological Activity

Yangambin is a furofuran lignan that has been isolated from plants such as the Annonaceae family, including: R. pickeli, R. exalbida and R. mucosa and Magnolia biondii. Yangambin is a selective PAF receptor antagonist that inhibits Ca2+ influx by modulating Ca2+ channels, resulting in a decrease in [Ca2+] in vascular smooth muscle cells and subsequent peripheral vasodilation. Yangambin exhibits anti-allergic activity against β-hexosaminidase with IC50 of 33.8 μM and anti-inflammatory activity with IC50 of 37.4 μM.

Yangambin Preparation Products And Raw materials

Raw materials

Preparation Products

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Yangambin Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354
Email
support@targetmol.com
Country
United States
ProdList
19973
Advantage
58

13060-14-5, YangambinRelated Search:


  • Lrioresinol B dimethyl ether
  • (1S,3aR,4S,6aR)-Tetrahydro-1,4-bis(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan
  • (+)-Yangabin
  • C10894
  • YANGAMBIN
  • (+)-O,O-Dimethyl lirioresinol B
  • (1S)-1β,4β-Bis(3,4,5-trimethoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan
  • (1β,5β)-2β,6β-Bis(3,4,5-trimethoxyphenyl)-3,7-dioxabicyclo[3.3.0]octane
  • [1S,(+)]-3aβ,4,6,6aβ-Tetrahydro-1β,4β-bis(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan
  • Lirioresinol B dimethyl ether
  • 1H,3H-Furo[3,4-c]furan, tetrahydro-1,4-bis(3,4,5-trimethoxyphenyl)-, (1S,3aR,4S,6aR)-
  • yangambin/Lrioresinol B dimethyl ether
  • (3S,3aR,6S,6aR)-3,6-bis(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan
  • inhibit,Calcium Channel,Yangambin,Ca channels,Ca2+ channels,Inhibitor
  • 13060-14-5
  • 13060-54-5